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pentobarbital will decrease the extent or influence of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic effect of elbasvir/grazoprevir may be lowered if coadministered with robust CYP3A inducers and it is thus contraindicated.Should you be allergic to Nembutal; any part of the drugs; or